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Routeplanner.app
St. James, MO
United States
St. James sits along I-44 in Missouri's Ozark foothills, about 90 minutes southwest of St. Louis. The town serves as a convenient stop for travelers crossing the state, with Highway 8 providing east-west connections and Highway 68 heading north to Jefferson City. The area's rolling hills and continental climate support several local wineries that have been making wine since the 1800s.