Seneca, SC

Seneca sits in South Carolina's Blue Ridge foothills, 40 miles southwest of Greenville via US 123. I-85 provides highway access at Exit 1, while local routes include SC 28 to Clemson and US 76 toward Georgia. The city serves as a gateway to Lake Keowee recreation areas and maintains its original 1873 railroad depot as a museum with a restored caboose still sitting on the tracks.