Santee, SC

Santee is a small lakeside town on Interstate 95 in South Carolina's Lowcountry, built around massive Lake Marion. Most visitors come for world-class fishing, especially for trophy blue catfish. I-95 provides easy access via exits 98 and 102, with US 301 running through downtown. The town hosts an annual Catfish Festival each April that's been running since 1985.

Airports closest to Santee, SC are Orangeburg Municipal Airport and Sumter Airport.