Table of contents
Overview
3About De Soto, MO
De Soto sits 45 miles southwest of St. Louis along the Meramec River in Jefferson County. Take I-270 to Highway 21 south through Festus to reach this city of 6,500. The area serves as a gateway between St. Louis suburbs and Missouri's wine country, with Highway 110 providing east-west access through town. Each September, the city hosts Drag Boat Races where 200-mph boats compete on the Meramec River.
Where is De Soto, MO on the map?
De Soto, MO is in United States, at 38.141, -90.561 - about 30 km south of Cedar Hill Lakes, MO.
How far is De Soto, MO from where I am?
Use your device location to see the distance to De Soto, MO, how long the drive takes, and directions from where you are.
Book
2Find hotels in De Soto, MO
Rent a car near De Soto, MO
Play
2Race a go-kart track in De Soto, MO
Race a go-kart track generated from the real streets of De Soto, MO.
De Soto ApexMediumPlay a pub crawl round in De Soto, MO
Nine holes from pub to pub through the real streets of De Soto, MO. Every cup is a bar somebody actually drinks in.
Explore
2Popular destinations close by
Nearby essentials
What is the closest airport to De Soto, MO?
The closest airport to De Soto, MO is St. Louis Lambert International Airport, 88 km (about 1 h 13 min by car).