How far is it from Clinton, NE, to Isabel, SD, ?

The distance between Clinton, NE, and Isabel, SD, is 268 mi by road.

How long does it take to drive from Clinton, NE, to Isabel, SD, ?

The drive from Clinton, NE, to Isabel, SD, takes approximately 6 h 5 min by car.

The fastest route from Clinton, NE, to Isabel, SD, covers 268 mi with a driving time of approximately 6 h 5 min.

Isabel, SD lies roughly to the north of Clinton, NE.

The drive from Clinton, NE to Isabel, SD mainly follows US 18, SD 73, SD 34. The longest single stretch is 86 mi on SD 73.

Distance: 268 miDuration: 6 h 5 min

Driving from Clinton, NE to Isabel, SD takes about 6 h 5 min via SD 73. The distance is 268 mi. The straight-line distance is 188 mi. Driving directions

Driving directions26 · 268 mi

The return trip from Isabel, SD to Clinton, NE covers roughly the same distance, 268 mi.

No notable attractions were found along this route.

Popular destinations close by

Distance and drive time are computed from OpenStreetMap road data with the OSRM routing engine. Updated August 7, 2026.

How far is it from Clinton, NE, {fromState} to Isabel, SD, {toState}?: The distance between Clinton, NE, {fromState} and Isabel, SD, {toState} is 268 mi by road.
How long does it take to drive from Clinton, NE, {fromState} to Isabel, SD, {toState}?: The drive from Clinton, NE, {fromState} to Isabel, SD, {toState} takes approximately 6 h 5 min by car.
What is the best route from Clinton, NE, {fromState} to Isabel, SD, {toState}?: The fastest route from Clinton, NE, {fromState} to Isabel, SD, {toState} covers 268 mi with a driving time of approximately 6 h 5 min.
Which direction is Isabel, SD from Clinton, NE?: Isabel, SD lies roughly to the north of Clinton, NE.
Which roads does the route from Clinton, NE to Isabel, SD follow?: The drive from Clinton, NE to Isabel, SD mainly follows US 18, SD 73, SD 34. The longest single stretch is 86 mi on SD 73.