How far is it from Siena to Brindisi?

The distance between Siena and Brindisi is 509 mi by road.

How long does it take to drive from Siena to Brindisi?

The drive from Siena to Brindisi takes approximately 8 h 35 min by car.

What is the best route from Siena to Brindisi?

The fastest route from Siena to Brindisi covers 509 mi with a driving time of approximately 8 h 35 min.

Which direction is Brindisi from Siena?

Brindisi lies roughly to the south-east of Siena.

Which roads does the route from Siena to Brindisi follow?

The drive from Siena to Brindisi mainly follows A1, A14, SS16. The longest single stretch is 186 mi on A14.

Which towns do you pass between Siena and Brindisi?

Towns on the route from Siena to Brindisi include Guidonia Montecelio, Chieti, Pescara, Bari.

Siena Brindisi

Distance: 509 miDuration: 8 h 35 min

Driving from Siena to Brindisi takes about 8 h 35 min via A14. The distance is 509 mi. The straight-line distance is 387 mi. EV charging is available along the route, including in Viterbo, Roma, Chieti, Pescara, Bari. Driving directions

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Driving directions46 · 509 mi

1 Depart onto Viale Don Giovanni Minzoni 140 yd
2 Turn left onto Viale Don Giovanni Minzoni 119 yd
3 Turn right onto Via Lippo Memmi 27 yd
4 Turn right onto Via Domenico Beccafumi 1 mi
5 Turn left onto Via Simone Martini 1 mi
6 At roundabout, take exit right onto Via Simone Martini 1 mi
7 Enter roundabout right onto Viale Pietro Toselli 82 yd
8 Exit roundabout slightly right onto Viale Pietro Toselli 1 mi
9 Enter roundabout slightly right onto Viale Pietro Toselli 48 yd
10 Exit roundabout slightly right onto Viale Pietro Toselli 1 mi
11 Enter roundabout slightly right onto Strada Levante 61 yd
12 Exit roundabout slightly right onto Strada Levante 1 mi
13 Enter roundabout right onto Strada Levante 48 yd

14 Exit roundabout slightly right onto Strada Levante 1 mi
15 Continue straight onto Strada ANAS 394 1 mi
16 Enter rotary slightly right onto Raccordo Autostradale Siena-Bettolle 91 yd
17 Exit rotary right onto Raccordo Autostradale Siena-Bettolle 27 mi
18 Take exit slightly right onto Svincolo di Bettolle 1 mi
19 Enter roundabout right onto Casello di Bettolle 94 yd
20 Exit roundabout right onto Casello di Bettolle 1 mi
21 Turn slightly right onto Svincolo di Bettolle 1 mi
22 Merge slightly left onto Autostrada del Sole 109 mi
23 Take exit slightly right 61 yd
24 Continue straight 1 mi
25 Keep slightly right 1 mi
26 Merge slightly left onto Strada dei Parchi 38 mi
27 Take exit slightly right onto Svincolo Direzionale Torano 1 mi
28 Continue straight onto Strada dei Parchi 71 mi
29 Keep slightly right 1 mi
30 Merge slightly left onto Autostrada Adriatica 183 mi
31 Keep slightly right onto Raccordo A14-Tangenziale di Bari 1 mi
32 Keep slightly left onto Raccordo A14-Tangenziale di Bari 3 mi
33 Keep slightly right 1 mi
34 Merge slightly left onto Tangenziale di Bari 7 mi
35 Continue straight onto Strada Statale 16 Adriatica 33 mi
36 Continue straight onto Strada Statale 379 Egnazia e delle Terme di Torre Canne 5 mi
37 Continue straight onto Egnazia e delle Terme di Torre Canne 28 mi
38 Take exit slightly right 1 mi
39 Turn straight onto Via Provinciale San Vito 1 mi
40 Turn slightly right onto Via Provinciale San Vito 1 mi
41 Enter roundabout right onto Via Provinciale San Vito 11 yd
42 Exit roundabout right onto Via Provinciale San Vito 1 mi
43 Continue straight onto Via de' Carpentieri 163 yd
44 Turn slightly right onto Via Bastioni San Giorgio 1 mi
45 Turn left onto Corso Umberto primo 25 yd
46 Arrive onto Corso Umberto primo

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The return trip from Brindisi to Siena covers roughly the same distance, 509 mi.

Driving directions from Siena to Brindisi
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Questions and answers

Along the way

Top attractions along the route

Rome Cruise Port Terminal
Ferry Terminals
Cruise Pirs Napoli
Ferry Terminals
Roma Cruise Terminal
Ferry Terminals

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Sources

Distance and drive time are computed from OpenStreetMap road data with the OSRM routing engine. Updated 16 August 2026.

Overview

Questions and answers

How far is it from Siena to Brindisi?: The distance between Siena and Brindisi is 509 mi by road.
How long does it take to drive from Siena to Brindisi?: The drive from Siena to Brindisi takes approximately 8 h 35 min by car.
What is the best route from Siena to Brindisi?: The fastest route from Siena to Brindisi covers 509 mi with a driving time of approximately 8 h 35 min.
Which direction is Brindisi from Siena?: Brindisi lies roughly to the south-east of Siena.
Which roads does the route from Siena to Brindisi follow?: The drive from Siena to Brindisi mainly follows A1, A14, SS16. The longest single stretch is 186 mi on A14.
Which towns do you pass between Siena and Brindisi?: Towns on the route from Siena to Brindisi include Guidonia Montecelio, Chieti, Pescara, Bari.

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