How far is it from Arequipa to Cusco?

The distance between Arequipa and Cusco is 315 mi by road.

How long does it take to drive from Arequipa to Cusco?

The drive from Arequipa to Cusco takes approximately 9 h 25 min by car.

What is the best route from Arequipa to Cusco?

The fastest route from Arequipa to Cusco covers 315 mi with a driving time of approximately 9 h 25 min.

Which direction is Cusco from Arequipa?

Cusco lies roughly to the north of Arequipa.

Which roads does the route from Arequipa to Cusco follow?

The drive from Arequipa to Cusco mainly follows PE-34E, CU-130, PE-3S. The longest single stretch is 127 mi on PE-34E.

Arequipa Cusco

Distance: 315 miDuration: 9 h 25 min

Driving from Arequipa to Cusco takes about 9 h 25 min via PE-34E. The distance is 315 mi. The straight-line distance is 201 mi. Driving directions

Attractions Car rental Popular routes Show more

Driving directions85 · 315 mi

1 Depart left onto Avenida Mariscal Cáceres 1 mi
2 Continue straight onto Avenida Salaverry 1 mi
3 Continue straight onto Paz Soldán 1 mi
4 Continue left onto Calle 28 de Julio 1 mi
5 Turn right onto Avenida de la Marina 1 mi
6 Turn slightly right 154 yd
7 Turn right 161 yd
8 Continue straight onto Avenida José Abelardo Quiñones 1 mi
9 Enter rotary slightly right onto Avenida José Abelardo Quiñones 13 yd
10 Exit rotary slightly right onto Avenida José Abelardo Quiñones 1 mi
11 Continue straight onto Avenida General José Trinidad Morán 167 yd
12 Turn left onto Calle Señor de la Caña 145 yd
13 Turn left onto Romaña 140 yd

14 At end of road, turn right onto Avenida Challapampa 1 mi
15 Turn right 1 mi
16 Continue straight onto Avenida Chachani 1 mi
17 At end of road, turn right onto Champallampa 15 yd
18 Turn left onto Avenida Prolongación Ejército 138 yd
19 Continue straight onto Avenida Pumacahua 1 mi
20 Turn left onto Avenida José Olaya 121 yd
21 Turn right onto Avenida Villa Hermosa 1 mi
22 Continue straight onto Avenida Tumbes 2 mi
23 Turn left onto Avenida Italia 1 mi
24 Turn right onto Vía de Evitamiento 1 mi
25 At end of road, turn left onto Avenida Aviación 1 mi
26 Continue straight onto Vía Interoceánica Sur - Tramo 5 143 yd
27 Turn left 65 yd
28 Turn right onto Avenida Ferrocarril 2 mi
29 Enter roundabout slightly right onto Avenida Apipa 9 yd
30 Exit roundabout right onto Avenida Apipa 1 mi
31 Enter roundabout right 69 yd
32 Exit roundabout slightly right 41 yd
33 Continue straight onto Autopista Cono Norte 3 mi
34 At end of road, turn left onto Vía Interoceánica Sur - Tramo 5 38 mi
35 Turn right 1 mi
36 Turn left 26 yd
37 Turn right onto Vía Interoceánica Sur - Tramo 5 1 mi
38 Keep slightly left onto Ruta 34 46 mi
39 Continue right onto Ruta 34 19 mi
40 Turn slightly left 25 mi
41 Enter roundabout slightly right 37 yd
42 Exit roundabout right 22 mi
43 Turn left 17 mi
44 Turn left 1 mi
45 Turn slightly right 3 mi
46 Turn left 8 mi
47 Turn right 3 mi
48 Turn straight 12 mi
49 At end of road, turn right 1 mi
50 Turn sharp left 3 mi
51 Turn slightly left 3 mi
52 Turn right 15 mi
53 Turn slightly right 3 mi
54 Continue straight 9 mi
55 Turn right 6 mi
56 Turn right 60 yd
57 Turn left 2 mi
58 Enter roundabout straight 37 yd
59 Exit roundabout straight 7 mi
60 Turn left 1 mi
61 Turn sharp left 1 mi
62 Turn right 6 mi
63 Turn slightly right 2 mi
64 Turn slightly right 4 mi
65 Turn straight 1 mi
66 Turn left 2 mi
67 Continue left 1 mi
68 At end of road, turn left onto Carretera Longitudinal de la Sierra Sur 12 mi
69 Continue straight onto Carretera Longitudinal de la Sierra Sur 14 mi
70 Keep slightly left onto Carretera Longitudinal de la Sierra Sur 2 mi
71 Turn straight onto Avenida Mariano Santos 1 mi
72 Continue straight onto Avenida Mariano Santos 1 mi
73 Continue straight onto Jirón Arica 1 mi
74 Merge slightly right onto Carretera Longitudinal de la Sierra Sur 10 mi
75 Keep slightly left onto Carretera Longitudinal de la Sierra Sur 7 mi
76 Continue straight onto Avenida Cusco 2 mi
77 Continue straight onto Carretera Longitudinal de la Sierra Sur 2 mi
78 Keep slightly right onto Vía de Evitamiento 6 mi
79 Turn left onto Avenida Velasco Astete 2 mi
80 Enter rotary right onto Avenida Los Pinos 126 yd
81 Exit rotary right onto Avenida Los Pinos 1 mi
82 Turn slightly right 58 yd
83 Turn left 18 yd
84 Turn left onto Avenida La Paz 11 yd
85 Arrive onto Avenida La Paz

View more details

The return trip from Cusco to Arequipa covers roughly the same distance, 315 mi.

Driving directions from Arequipa to Cusco
Top attractions along the route
Find hotels near Cusco
Rent a car near Arequipa
Popular routes from destination
Questions and answers

Along the way

Top attractions along the route

No notable attractions were found along this route.

Book

Find hotels near Cusco

Rent a car near Arequipa

Explore

Popular routes from destination

Sources

Distance and drive time are computed from OpenStreetMap road data with the OSRM routing engine. Updated 7 September 2026.

Overview

Questions and answers

How far is it from Arequipa to Cusco?: The distance between Arequipa and Cusco is 315 mi by road.
How long does it take to drive from Arequipa to Cusco?: The drive from Arequipa to Cusco takes approximately 9 h 25 min by car.
What is the best route from Arequipa to Cusco?: The fastest route from Arequipa to Cusco covers 315 mi with a driving time of approximately 9 h 25 min.
Which direction is Cusco from Arequipa?: Cusco lies roughly to the north of Arequipa.
Which roads does the route from Arequipa to Cusco follow?: The drive from Arequipa to Cusco mainly follows PE-34E, CU-130, PE-3S. The longest single stretch is 127 mi on PE-34E.

Table of contents